GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BRCA | cis | rs111803315 | 1 | rs111882043 | chr14:59899356 | JKAMP | chr14:59951161-59972080:+ | 0.31 | 5.36 | 1.04E-7 | Schizophrenia |
| BRCA | cis | rs56322409 | 1 | rs11188394 | chr10:97365458 | ENTPD1 | chr10:97471536-97637022:+ | 0.15 | 5.08 | 4.53E-7 | Blood metabolite levels |
| BRCA | cis | rs56322409 | 1 | rs11188396 | chr10:97367510 | ENTPD1 | chr10:97471536-97637022:+ | 0.17 | 5.79 | 9.16E-9 | Blood metabolite levels |
| BRCA | cis | rs56322409 | 1 | rs11188398 | chr10:97369093 | ENTPD1 | chr10:97471536-97637022:+ | 0.17 | 5.84 | 7.09E-9 | Blood metabolite levels |
| BRCA | cis | rs56322409 | 1 | rs11188400 | chr10:97371327 | ENTPD1 | chr10:97471536-97637022:+ | 0.17 | 5.8 | 8.63E-9 | Blood metabolite levels |
| BRCA | cis | rs56322409 | 1 | rs11188406 | chr10:97390195 | ENTPD1 | chr10:97471536-97637022:+ | 0.17 | 5.81 | 8.05E-9 | Blood metabolite levels |
| BRCA | cis | rs56322409 | 1 | rs11188407 | chr10:97390533 | ENTPD1 | chr10:97471536-97637022:+ | 0.17 | 5.83 | 7.23E-9 | Blood metabolite levels |
| BRCA | cis | rs56322409 | 1 | rs11188411 | chr10:97397344 | ENTPD1 | chr10:97471536-97637022:+ | 0.16 | 5.6 | 2.75E-8 | Blood metabolite levels |
| BRCA | cis | rs56322409 | 1 | rs11188417 | chr10:97411680 | ENTPD1 | chr10:97471536-97637022:+ | -0.18 | -6.18 | 9.36E-10 | Blood metabolite levels |
| BRCA | cis | rs948562 | 1 | rs111901203 | chr11:58297542 | CNTF | chr11:58390146-58393203:+ | 0.17 | 3.61 | 0.000319 | Lymphoma |
| BRCA | cis | rs17112901 | 1 | rs11190466 | chr10:102061908 | PKD2L1 | chr10:102047903-102090243:- | 0.22 | 4.33 | 1.67E-5 | Obesity-related traits |
| BRCA | cis | rs11190604 | 1 | rs11190540 | chr10:102202629 | SEC31B | chr10:102246403-102289636:- | -0.28 | -10.46 | 2.0E-24 | Palmitoleic acid (16:1n-7) plasma levels |
| BRCA | cis | rs11190604 | 1 | rs11190541 | chr10:102203071 | SEC31B | chr10:102246403-102289636:- | -0.28 | -10.35 | 5.68E-24 | Palmitoleic acid (16:1n-7) plasma levels |
| BRCA | cis | rs11190604 | 1 | rs11190551 | chr10:102204734 | SEC31B | chr10:102246403-102289636:- | -0.28 | -10.43 | 2.53E-24 | Palmitoleic acid (16:1n-7) plasma levels |
| BRCA | cis | rs11190604 | 1 | rs11190552 | chr10:102206607 | SEC31B | chr10:102246403-102289636:- | -0.28 | -10.23 | 1.66E-23 | Palmitoleic acid (16:1n-7) plasma levels |